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The complete loss of smell — anosmia  — can be temporary or permanent, depending on the cause. Loss of smell caused by a common cold will clear up on its own. Loss of smell related to an obstruction of the nasal passage, such as polyps, will clear up when the obstruction is removed. Loss of smell related to other causes, such as aging or a brain tumor, may be permanent. Anosmia isn't necessarily a serious condition in and of itself, but an intact sense of smell is necessary to fully taste foods. So loss of smell could cause you to lose interest in eating, leading to weight loss, malnutrition or even depression. Loss of smell also prevents you from smelling things like spoiled food or smoke. CAUSES Acute sinusitis     (sinus infection) Loss of smell due to problems with the inner lining of your nose Anosmia can be caused by temporary or permanent irritation, or destruction of the mucus membranes lining the inside of your nose. This can be caused by: Hay fever Common cold Influen